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KMID : 0438219790160010307
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Korea University Medical Journal
1979 Volume.16 No. 1 p.307 ~ p.315
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Muscle-Relaxants on the Intraocular pressure in man during general anesthesia
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Abstract
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The purpose of this experiments were to evaluate the effect of muscle relaxants on the intraocular pressure during general anesthesia for intraocular surgery.
Forty patients in American Society of Anesthesiologists Physical status 1 and U aged from 19 to 60 years were studied during anesthesia far elective surgery aril give no history of eye disease. All were premedicated with 59mg of meperidine and 0.5mg of atropine.
Before induction intraocular pressure was measured and defined control value. Anesthesia were induced with 2.5% thiopental sodium and succinylcholine chloride and intraocular pressure was measured after endotracheal intubation. Anesthesia were maintained by morphine, haloperidol, nitrous oxide, and oxygen. Tubocurarine and pancuronium were administered on the return of spontaneous respiration following succinylcholine chloride.
Subsequent measurement were 5,10,23 minutes after tubocurarine and pancuronium administration respectively.
The results were as follows;
1. Succinylcholine chloride caused a significant rise in intraocular pressure.
2. Pancuronium caused a significa% decrease in intraocular pressure.
3. Tubocurarine caused a significant decrease in intraocular pressure.
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